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Nurse Practitioner - Physician Assistant

PublishedPublished: 10/18/2026

Physician Assistant / Nurse Practitioner

Part-Time | Melville, NY

About Us

Unique and exciting opportunity to join a thriving, growing private practice with two established locations in Lower Manhattan and Melville, Long Island. New York Ketamine Infusions (NYKI) is seeking a dedicated, compassionate, and self-motivated Physician Assistant (PA) or Nurse Practitioner (NP) to join our team at our Melville office.

Our practice provides specialized treatments for patients with treatment-resistant depression, including ketamine infusions and Spravato® (esketamine) treatments.

The successful candidate will work directly with patients throughout their treatment experience, including conducting consultations, initiating and monitoring IV infusions, administering and monitoring Spravato treatments, assessing patient progress, and responding to patient needs. This role requires strong clinical skills, excellent patient care, attention to detail, and the ability to work independently while collaborating with physicians and a supportive clinical team.

We are looking for a healthcare professional who is passionate about improving patients' quality of life through innovative, specialized mental health treatment options.

Main Duties and Responsibilities

  • Establish IV access and administer medications in accordance with established protocols and physician orders.
  • Conduct patient consultations and provide education regarding treatment options, procedures, and expectations.
  • Provide care for patients receiving ketamine infusions for treatment-resistant depression.
  • Administer Spravato® (esketamine) treatments in accordance with prescribing requirements, established clinical protocols, and applicable REMS program requirements.
  • Monitor patients throughout infusion treatments, Spravato administration, and recovery, assessing vital signs, clinical response, and potential adverse reactions.
  • Provide appropriate patient monitoring and observation following Spravato administration, including assessment for sedation, dissociation, and changes in blood pressure.
  • Recognize and respond promptly and confidently to medical emergencies and adverse reactions.
  • Maintain accurate, timely, and complete medical records and treatment documentation.
  • Collaborate with supervising physicians and other clinical team members to ensure safe, effective, and high-quality patient care.
  • Provide compassionate patient support and maintain a professional, reassuring treatment environment.
  • Follow all applicable clinical guidelines, safety protocols, regulatory requirements, and practice policies.

Minimum Requirements

  • Minimum of two years of clinical experience with IV placement and medication administration.
  • Minimum of two years of experience as a Physician Assistant or Nurse Practitioner.
  • Current New York State license and applicable certification as a Physician Assistant or Nurse Practitioner.
  • Graduate degree from an accredited Physician Assistant or Nurse Practitioner program.
  • Current BLS/ACLS and CPR certifications, as applicable to the role.
  • Strong clinical assessment, patient monitoring, and emergency response skills.
  • Ability to work independently within the scope of practice and collaboratively under physician supervision.
  • Excellent communication, organizational, and patient-care skills.
  • Compassionate, professional, and attentive approach to patients receiving specialized mental health treatments.

Preferred Qualifications

  • ICU or emergency department experience strongly preferred.
  • Experience administering ketamine infusions or other infusion-based therapies.
  • Experience with Spravato® (esketamine) administration and REMS program requirements.
  • Experience caring for patients with treatment-resistant depression or other complex mental health conditions.

Position Details

  • Location: Melville, Long Island, NY
  • Employment Type:Part-Time
  • Practice Setting: Private outpatient specialty practice

Join our team and help provide compassionate, specialized care to patients seeking innovative treatment options for depression.

EOE Statement

We are an equal employment opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, national origin, disability status, protected veteran status or any other characteristic protected by law.